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1. (DK1904113) NEUROBESKYTTENDE EFFEKTIV FORBINDELSE

Office : Denmark
Application Number: 06785518 Application Date: 23.06.2006
Publication Number: 1904113 Publication Date: 21.03.2016
Grant Number: Grant Date: 21.03.2016
Publication Kind : T3
Prior PCT appl.: Application Number:US2006024656 ; Publication Number: Click to see the data
IPC:
A61K 48/00
A61K 38/18
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
Applicants: TissueGene, Inc.
Inventors: KIM, Hyoung, Chun
Priority Data: 595342 P 23.06.2005 US
Title: (DA) NEUROBESKYTTENDE EFFEKTIV FORBINDELSE
Abstract:
(EN) The present application discloses a method of preventing degeneration of nerve, which includes: a) generating a recombinant viral or plasmid vector comprising a DNA sequence encoding a member of a transforming growth factor superfamily or neurotrophic factor proteins operatively linked to a promoter; b) transfecting in vitro a population of cultured cells with the recombinant vector, resulting in a population of the cultured cells; and c) transplanting the transfected cells to an area near an injured nerve, such that expression of the DNA sequence within the area near the injured nerve causes prevention of degeneration of the nerve.
Also published as:
KR1020080038310KR1020100074340EP1904113JP2009506982CN101232904CA2613551
JP2014088425KR1020130101595KR1020140132010ES2562243KR1020160021458CN106177996
AU2006261889AU2010257453IN10145/DELNP/2007KR1020180057737WO/2007/002512