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1. DE102018130469 - Transdermales therapeutisches System mit Diffusionsbarriere

Office Germany
Application Number 102018130469
Application Date 30.11.2018
Publication Number 102018130469
Publication Date 04.06.2020
Publication Kind A1
IPC
A61L 15/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42Use of materials characterised by their function or physical properties
44Medicaments
A61K 9/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
A61F 13/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
13Bandages or dressings; Absorbent pads
02Adhesive plasters or dressings
CPC
A61K 9/703
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
A61K 9/7046
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
A61K 9/7084
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Applicants LTS Lohmann Therapie-Systeme AG
Inventors Reum Nico
Emgenbroich Marco
Wiedersberg Sandra
Agents Davepon Björn
Title
(DE) Transdermales therapeutisches System mit Diffusionsbarriere
Abstract
(DE)

Die vorliegende Erfindung betrifft ein transdermales therapeutisches System (1) umfassend • eine Wirkstoffträgerschicht (2) mit mindestens einer auf der Wirkstoffträgerschicht (2) aufgebrachten wirkstoffhaltigen Polymermatrix (3) enthaltend wenigstens einen Haftklebstoff und zumindest einen pharmakologisch aktiven und über die menschliche oder tierische Haut resorbierbaren Wirkstoff, sowie • eine mit einem wirkstofffreien Haftklebstoff (7) weitestgehend vollflächig beschichtete Haftträgerschicht (6), die mittels des wirkstofffreien Haftklebstoffs (7) unmittelbar auf der der wirkstoffhaltigen Polymermatrix (3) abgewandten Flachseite der Wirkstoffträgerschicht (2) aufgeklebt ist, wobei die Haftträgerschicht (6) die Wirkstoffträgerschicht (2) randseitig umlaufend überragt, wobei das System dadurch gekennzeichnet ist, dass zwischen der wirkstoffhaltigen Polymermatrix (3) und dem wirkstofffreien Haftklebstoff (7) ein umlaufender Bereich verringerter Beschichtungsdicke (4) an wirkstoffhaltiger Polymermatrix (3) und/oder an dem wirkstofffreien Haftklebstoff (7) vorgesehen ist. Die Erfindung betrifft ferner die Verwendung dieses transdermalen therapeutischen Systems und ein Kit, welches dieses enthält. embedded image

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