DE202012002792 Zusammensetzung für die nasale Applikation mit verbesserter Stabilität

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Germany

Application Number 202012002792

Application Date 20.03.2012

Publication Number 202012002792

Publication Date 28.02.2013

Publication Kind U1

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Applicants KLOSTERFRAU MCM VETRIEB GMBH

Priority Data 102011122588 30.12.2011 DE

Title

(DE) Zusammensetzung für die nasale Applikation mit verbesserter Stabilität

Abstract

(DE)

Zusammensetzung, insbesondere pharmazeutische Zusammensetzung, vorzugsweise für die topische, insbesondere nasale, bevorzugt intranasale Applikation, insbesondere für die Behandlung von Rhinitiden, wobei die Zusammensetzung a) mindestens ein imidazolinbasiertes alpha-Sympathomimetikum oder dessen physiologisch unbedenkliches Salz; und b)(b1) Pantothenol (Dexpanthenol) oder dessen physiologisch unbedenkliche Ester und/oder (b2) Pantothensäure oder deren physiologisch unbedenkliche Salze enthält, dadurch gekennzeichnet, dass der pH-Wert der Zusammensetzung im Bereich von 5,0 bis 6,2 eingestellt und/oder konstantgehalten ist.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
64	Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
64	Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
16	Amides, e.g. hydroxamic acids
164	of a carboxylic acid with an aminoalcohol, e.g. ceramides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
185	Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19	Carboxylic acids, e.g. valproic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41	having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
4164	1,3-Diazoles
4174	Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole

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1. DE202012002792 - Zusammensetzung für die nasale Applikation mit verbesserter Stabilität

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11	Drugs for disorders of the respiratory system
02	Nasal agents, e.g. decongestants

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06	Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
16	containing nitrogen, ; e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
18	Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
186	Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06	Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
22	Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30	Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
36	Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin