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1. CR36/9567 - FORMULACION DE LIBERACION PROLONGADA DE PRINCIPIOS ACTIVOS QUE PRESENTAN UNA SOLUBILIDAD DEPENDIENTE DEL PH

Office Costa Rica
Application Number 9567
Application Date 06.12.2007
Publication Number 36/9567
Publication Date 20.02.2008
Publication Kind A
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
12
Carboxylic acids; Salts or anhydrides thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
30
Organic coatings
36
containing carbohydrates or derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61K 47/12
A61K 9/24
A61K 9
A61K 9/36
A61K 31/437
CPC
A61K 9/2013
A61K 9/2054
A61K 9/209
A61K 31/437
Applicants SANOFI-AVENTIS
SANOFI-AVENTIS
SANOFI-AVENTIS
SANOFI-AVENTIS
SANOFI-AVENTIS
SANOFI-AVENTIS
SANOFI-AVENTIS
Inventors GERARD ALAUX
FREDERIC ANDRE
GARETH LEWIS
VERONIQUE SERRE
GERARD ALAUX
FREDERIC ANDRE
GARETH LEWIS
VERONIQUE SERRE
Priority Data 0506539 28.06.2005 FR
Title
(ES) FORMULACION DE LIBERACION PROLONGADA DE PRINCIPIOS ACTIVOS QUE PRESENTAN UNA SOLUBILIDAD DEPENDIENTE DEL PH
Abstract
(ES)
La invención se refiere a una formualción nueva para una liberación prolongada de un principio activo qu epresenta una solubilidad dependiente del PH. La formulación de l ainvención comprende un excipiente matricial a base de polímero hidrófilo que contiene una dosis determinada del principio activo, y también comprende uno o varios agentes acidificantes en forma de una sal ácida de un ácido orgánico.