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1. (CN102711826) Methods and compositions for modulating HEPSIN activation of macrophage-stimulating protein

Office : China
Application Number: 201080055076.4 Application Date: 21.10.2010
Publication Number: 102711826 Publication Date: 03.10.2012
Grant Number: 102711826 Grant Date: 29.03.2017
Publication Kind : B
Prior PCT appl.: Application Number:PCTUS2010053600 ; Publication Number:2011050194 Click to see the data
IPC:
A61K 39/395
C12Q 1/37
G01N 33/53
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
34
involving hydrolase
37
involving peptidase or proteinase
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
CPC:
C07K 16/40
A61K2039/505
C07K2317/76
G01N 33/68
G01N2333/705
G01N2333/96433
G01N2500/02
Applicants: 霍夫曼-拉罗奇有限公司
Inventors: R.甘尼桑
D.科赫霍弗
Agents: 北京坤瑞律师事务所 11494
Priority Data: 61/253,990 22.10.2009 US
Title: (EN) Methods and compositions for modulating HEPSIN activation of macrophage-stimulating protein
(ZH) 用于调控巨噬细胞刺激性蛋白的HEPSIN活化的方法和组合物
Abstract: front page image
(EN) The invention provides methods and compositions for modulating hepsin activity and the MSP/Ron pathway, in particular by regulating pro-MSP activation by hepsin.
(ZH) 本发明提供了用于调控hepsin活性和MSP/Ron途径的方法和组合物,特别是通过调节hepsin对MSP原的活化来进行。
Also published as:
EP2490718US20120282271JP2013507967CA2778442RU2012120863MX2012004617
RU0002539772KR1020120105446ES2564207BR112012009409IN3566/CHENP/2012WO/2011/050194