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1. CN102300557 - Drug delivery system for use in the treatment of vessel-related pathologies

Office China
Application Number 201080013481.X
Application Date 26.01.2010
Publication Number 102300557
Publication Date 28.12.2011
Publication Kind A
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
197
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
198
Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A61K 9/127
A61K 31/198
A61K 47/48
CPC
A61K 9/1271
A61K 9/1272
A61K 41/0028
A61K 41/0071
A61K 47/6913
Applicants Academisch Medisch Ct
阿卡戴密克医学中心
Inventors Heger Michal
麦克海洛
Agents he wei yuan yinghua
长沙正奇专利事务所有限责任公司 43113
长沙正奇专利事务所有限责任公司 43113
Priority Data 09151332.5 26.01.2009 EP
Title
(EN) Drug delivery system for use in the treatment of vessel-related pathologies
(ZH) 用于治疗血管疾病的给药系统
Abstract
(EN)
The present invention relates to a drug delivery system for use in the treatment of vessel-related pathologies, comprising a drug delivery platform that comprises at least one compound capable of exerting an effect on the formation and/or maintenance of a thrombus in the vessel to be treated. The platform is preferably formed by liposomes that are sterically stabilized by grafting of poly(ethylene glycol) onto the liposome surface. The compound is suitably tranexamic acid. The drug delivery system is preferably used for the treatment of port wine stains.

(ZH)

本发明涉及一种用于治疗血管疾病的给药系统,包含一个给药平台,该给药平台包括至少一个能在待治疗血管血栓的形成和维护施加影响的化合物。该给药平台是空间位阻稳定的脂质体形成。该空间位阻稳定可以通过在脂质体表面嫁接聚乙烯(乙二醇)来实现。该化合物为止血环酸。该给药系统用于治疗葡萄酒色斑。