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1. (CN101282762) Methods and compositions for improving pregnancy outcome

Office : China
Application Number: 200680031124.X Application Date: 05.07.2006
Publication Number: 101282762 Publication Date: 08.10.2008
Publication Kind : A
Prior PCT appl.: Application Number:PCTAU2006000939 ; Publication Number:2007003007 Click to see the data
IPC:
A61P 15/08
A61K 31/355
A61K 33/30
A61K 31/01
A61K 31/375
A61K 36/8962
A61K 31/122
A61K 33/04
A61P 15/10
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
08
for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
353
3,4-Dihydrobenzopyrans, e.g. chroman, catechin
355
Tocopherols, e.g. vitamin E
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
30
Zinc; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
01
Hydrocarbons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
365
Lactones
375
Ascorbic acid, i.e. vitamin C; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
88
Liliopsida (monocotyledons)
896
Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
8962
Allium, e.g. garden onion, leek, garlic or chives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
12
Ketones
122
having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
04
Sulfur, selenium or tellurium; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
10
for impotence
CPC:
A61K 33/04
A61K 31/01
A61K 31/122
A61K 31/355
A61K 31/375
A61K 33/30
A61K 36/81
A61K 36/82
A61K 36/8962
A61K 45/06
Applicants: Adelaide Fertility Ct Pty Ltd.
生产力技术控股有限公司
Inventors: Tremellen Kelton Paul
K·P·特梅伦
Agents: fanzheng
上海专利商标事务所有限公司
Priority Data: 60/696,746 05.07.2005 US
Title: (EN) Methods and compositions for improving pregnancy outcome
(ZH) 改善妊娠结局的方法和组合物
Abstract: front page image
(EN) The present invention relates to a method of increasing pregnancy rate in a female subject, the female subject or an oocyte for introduction into the female subject being fertilized by a sperm from a male subject. The method includes the steps of administering to the male subject prior to fertilization: (i) an effective amount of an anti-oxidant agent; and (ii) an effective amount of an agent that reduces inflammation in the male reproductive tract and/or an effective amount of an agent that increases testicular testosterone concentration.
(ZH)

本发明涉及一种提高女性对象妊娠率的方法,所述女性对象或引入该女性对象的卵母细胞已被来自男性对象的精子受精。该方法包括在受精前给予该男性对象以下试剂的步骤:(i)有效量的抗氧化剂;和(ii)有效量的减轻男性生殖道内炎症的试剂和/或有效量的提高睾丸睾酮浓度的试剂。


Also published as:
NZ562925KR1020080038331EP1909911JP2008544994US20090081177CA2642008
CA2614210EA200800260AU2006265777AU2008217001AU2009100215ID048.3033
IN367/DELNP/2008WO/2007/003007