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1. (CN1738606) Improved oral delivery of peptides

Office : China
Application Number: 200480002372.2 Application Date: 21.01.2004
Publication Number: 1738606 Publication Date: 22.02.2006
Grant Number: 100508957 Grant Date: 08.07.2009
Publication Kind : C
Prior PCT appl.: Application Number:PCTUS2004001633 ; Publication Number:2004064758 Click to see the data
IPC:
A61K 9/28
A61K 9/30
A61K 38/02
A61K 38/09
A61K 38/23
A61K 38/26
A61K 38/28
A61K 38/29
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
30
Organic coatings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
02
Peptides of undefined number of amino acids; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08
Peptides having 5 to 11 amino acids
09
Luteinising hormone-releasing hormone (LHRH); Related peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
23
Calcitonins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
26
Glucagons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
28
Insulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
29
Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
Applicants: Unigene Lab Inc.
尤尼金实验室股份有限公司
Inventors: Mehta Nozer M.
N·M·梅达
Stern William
W·斯特恩
Gilligan James P.
J·P·吉力干
Agents: chen wenjing
上海专利商标事务所有限公司
Priority Data: 10761481 20.01.2004 US
60/441,856 21.01.2003 US
Title: (EN) Improved oral delivery of peptides
(ZH) 肽经口输递的改进
Abstract:
(EN) Bioavailability of peptide active agents to be administered orally is enhanced by a pharmaceutical composition providing an active peptide that is amidated at a site that is not naturally amidated.
(ZH)

通过一种提供在非天然酰胺化位点被酰胺化的活性肽的药物组合物提高经口给药的活性肽生物利用度。


Also published as:
IL169615EP1585503JP2006517542CA2512824ES2563489DK1585503
AU2004206949WO/2004/064758