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1. CN1738651 - Contrast media formulations having improved biological tolerance

Office
China
Application Number 200380109016.6
Application Date 07.11.2003
Publication Number 1738651
Publication Date 22.02.2006
Publication Kind A
IPC
A61K 49/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
CPC
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61K 49/0433
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
0433containing an organic halogenated X-ray contrast-enhancing agent
A61K 49/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
A61K 49/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
Applicants Biophysica Inc.
生物物理公司
Inventors Sovak Milos
米洛斯·索瓦克
Terry Ronald C.
艾伦·L·塞利格森
Seligson Allen L.
罗纳德·C·特里
Agents zhao renlin zhang bengyuan
北京市柳沈律师事务所
北京市柳沈律师事务所
Priority Data 10701586 05.11.2003 US
60/432,879 12.12.2002 US
Title
(EN) Contrast media formulations having improved biological tolerance
(ZH) 具有改善的生物耐受性的造影剂制剂
Abstract
(EN) This invention comprises new formulations of radiographic contrast media including dimeric non-ionic media, with an organic amine and a carboxylic acid. Formulations of this invention increase the biological tolerance of such media, thereby increasing their safety.
(ZH)

本发明包括新的放射照相造影剂制剂,包括二聚非离子造影剂与有机胺和羧酸。本发明的制剂可增加这类造影剂的生物耐受性,由此增加其安全性。