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1. (CN1200033) Method of producing multi-layer medicaments in solid form for oral or rectal administration

Office : China
Application Number: 96197791.4 Application Date: 23.10.1996
Publication Number: 1200033 Publication Date: 25.11.1998
Grant Number: 1092955 Grant Date: 23.10.2002
Publication Kind : C
Prior PCT appl.: Application Number:PCTEP9604601 ; Publication Number:9715293 Click to see the data
IPC:
A61K 9/24
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
CPC:
A61J 3/10
A61J 2200/20
A61K 9/209
A61K 9/2095
A61K 9/2893
A61K 31/07
A61K 31/167
A61K 31/192
A61K 31/277
A61K 31/355
A61K 31/375
A61K 31/401
A61K 31/4422
A61K 31/52
A61K 31/522
A61K 31/616
B30B 11/14
B30B 11/16
B30B 11/18
B30B 11/34
B30B 15/308
Applicants: BASF Aktiengesellschaft
巴斯福股份公司
Inventors: J. Breitenbach
J·伯莱顿巴赫
A. P. Haertl
A·P·哈托
J. Hofmann
J·霍夫曼
J·罗森伯格
M·希索
H·D·采特勒
Agents: huang zexiong
中国国际贸易促进委员会专利商标事务所
Priority Data: 19539361.9 23.10.1995 DE
Title: (EN) Method of producing multi-layer medicaments in solid form for oral or rectal administration
(ZH) 口服或直肠给药的多层固体药物剂型的生产方法
Abstract: front page image
(EN) The invention concerns a method of producing multi-layer medicaments in solid form for oral or rectal administration. At least two substances, which each comprise a thermoplastic, pharmacologically acceptable polymer binder which is soluble or can swell in a physiological environment, at least one of the substances comprising a pharmaceutical active substance, are coextruded and the coextruded multi-layer material is shaped to form the desired medicament.
(ZH)

本发明涉及一种口服或直肠给药的多层固体药物剂型的生产方法,该方法包括共挤出至少两种在各种情况下均包含热塑性、生理可接受的聚合物粘合剂的组合物,所述粘合剂在生理环境中可溶解或溶胀,并且至少一种组合物含有药物活性成分,然后成形共挤出的多层物料,形成所需药物剂型。


Also published as:
CZPV1998-1242NO19981793ES2175139EP0857062US6120802JPH11513697
CA2232356PT857062KR1019990066978DK0857062AU1996074912MYPI 96004363
BG102313WO/1997/015293