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1. CN114008720 - INHALER SYSTEM

Office
China
Application Number 202080032345.9
Application Date 30.04.2020
Publication Number 114008720
Publication Date 01.02.2022
Publication Kind A
IPC
G16H 50/30
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
30for calculating health indices; for individual health risk assessment
A61M 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15Inhalators
A61B 5/087
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
08Measuring devices for evaluating the respiratory organs
087Measuring breath flow
G16H 20/13
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
20ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
10relating to drugs or medications, e.g. for ensuring correct administration to patients
13delivered from dispensers
CPC
G16H 50/30
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
30for calculating health indices; for individual health risk assessment
A61B 5/087
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
087Measuring breath flow
G16H 20/13
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
20ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
10relating to drugs or medications, e.g. for ensuring correct administration to patients
13delivered from dispensers
A61K 9/0073
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
007Pulmonary tract; Aromatherapy
0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy;
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
Applicants NORTON (WATERFORD) LIMITED
诺顿(沃特福特)有限公司
Inventors MILTON-EDWARDS MARK
马克·米尔顿-爱德华
SAFIOTI GUILHERME
吉勒姆·萨福提
GRANOVSKY LENA
莉娜·格拉诺夫斯基
REICH MICHAEL
迈克尔·赖希
Agents 上海天翔知识产权代理有限公司 31224
Priority Data 1906078.9 30.04.2019 GB
1910776.2 29.07.2019 GB
1919070.1 20.12.2019 GB
1919076.8 20.12.2019 GB
1919081.8 20.12.2019 GB
2003534.1 11.03.2020 GB
Title
(EN) INHALER SYSTEM
(ZH) 吸入器系统
Abstract
(EN) Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises a first inhaler (100) for delivering a rescue medicament to the subject. The rescue medicament may be suitable for treating the subject's acute respiratory disease, for example by effecting rapid dilation of the bronchi and bronchioles upon inhalation of the medicament. The first inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processor (14) configured to determine a number of times of rescue inhalation during a first time period, and receive the parameter measured for at least some of the rescue and/or routine inhalation. The processor then determines, using a weighted model, the probability of the asthma exacerbation based on the number of times of the rescue inhalation and the parameters. The model is weighted such that the number of times of the rescue inhalation is more significant in the probability determination than the parameters. Further provided is a method for determining the probability of an asthma exacerbation in a subject, which method employs the weighted model.
(ZH) 提供了一种用于测定受试者的哮喘恶化概率的系统(10)。系统包括用于向受试者递送抢救药剂的第一吸入器(100)。所述抢救药剂可适用于治疗受试者的急性呼吸道疾病,例如通过在所述药剂吸入后实现支气管和细支气管快速扩张来治疗。第一吸入器具有使用检测系统(12B),所述使用检测系统配置成测定受试者使用第一吸入器进行的抢救吸入。系统可选地包含用于在常规吸入期间向受试者递送维持药剂的第二吸入器。传感器系统(12A)配置成测量与抢救吸入期间和/或当系统包含第二吸入器时进行常规吸入期间的气流相关的参数。系统进一步包括处理器(14),所述处理器配置成测定在第一时间段期间发生抢救吸入的次数,并接收针对至少一些抢救和/或常规吸入所测量的参数。处理器然后使用加权模型基于抢救吸入次数和参数测定哮喘恶化概率。对模型赋予权重,使得抢救吸入次数在概率测定时的意义大于参数。进一步提供了一种用于测定受试者的哮喘恶化概率的方法,所述方法采用加权模型。