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1. CN113825518 - METHODS OF PURIFYING ALLERGEN EXTRACT

Office
China
Application Number 201980092803.5
Application Date 26.03.2019
Publication Number 113825518
Publication Date 21.12.2021
Publication Kind A
IPC
A61K 35/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
35Fat tissue; Adipocytes; Stromal cells; Connective tissues 
A61K 35/646
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
63Arthropods
646Arachnids, e.g. spiders, scorpions, ticks or mites
A61K 35/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
A61K 35/68
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
68Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
CPC
A61K 35/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
35Fat tissue; Adipocytes; Stromal cells; Connective tissues
A61K 35/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
A61K 35/646
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
63Arthropods
646Arachnids, e.g. spiders, scorpions, ticks or mites
A61K 35/68
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
68Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
A61K 36/63
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
A61K 36/899
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
Applicants LABORATORIOS LETI SLU
莱蒂生物制药公司
Inventors ROMAN-ESCUTIA MARTA
M·罗曼·埃斯库蒂亚
MORALES MARIA
M·莫拉莱斯
GALLEGO MARIA TERESA
M·T·加列戈
CARNES SANCHEZ JERONIMO
J·卡内尔·桑切斯
Agents 北京坤瑞律师事务所 11494
Priority Data 19382030.5 17.01.2019 EP
Title
(EN) METHODS OF PURIFYING ALLERGEN EXTRACT
(ZH) 纯化过敏原提取物的方法
Abstract
(EN) The invention relates to processes for producing semi-purified and purified allergen extracts and pharmaceutical compositions and vaccines for use in the diagnosis and treatment of allergy. In one aspect of the invention, a process for producing a depigmented allergen extract is provided, the process comprising: a) basifying a native allergen extract; and b) removing molecules having a molecular size of less than 3.5 kDa; and c) adjusting the pH to neutrality; thereby to produce a depigmented allergen extract.
(ZH) 本发明涉及生产用于诊断和治疗过敏症的半纯化和纯化过敏原提取物以及药物组合物和疫苗的方法。在本发明的一个方面,提供了一种生产脱色过敏原提取物的方法,所述方法包括:a)碱化天然过敏原提取物;并且b)去除分子大小小于3.5kDa的分子;并且c)调节pH至中性;从而产生脱色过敏原提取物。
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