(EN) The inventions relates to an injectable macroporous hydrogels, and a method for generating a macroporous hydrogel. In a first step, an aqueous solution of two solutes is produced. The first solute is a polymer that can be cross-linked and is a derivative of polyethylene glycol (PEG) or polyoxazoline (POx), and the second solute is a kosmotropic agent. In a second step, a cross-linking agent is added to the solution, this simultaneously initiates gelation of the polymer and phase-separation, thus creating the macroporous hydrogel. The invention further relates to the macroporous hydrogel, which can be obtained by the inventive method. The macroporous hydrogel is comprised of a cross-linked polymer which is the derivative of polyethylene glycol (PEG) or polyoxazoline (POx). The hydrogel exhibits interconnected macropores with a size of 200 nm to 1000 micrometers, particularly 500 nm to 100 micrometers and is characterized by a pH of of 7,0 to 8,0, particularly approx. 7,4.
(ZH) 本发明涉及可注射大孔水凝胶，并且还涉及生成大孔水凝胶的方法。在第一步，产生两种溶质的水性溶液。所述第一溶质是可以交联的聚合物，并且是聚乙二醇(PEG)或聚噁唑啉(POx)的衍生物，所述第二溶质是有序构造性试剂。在第二步，向溶液添加交联剂。这同时引发所述聚合物的胶凝和相分离，由此生成大孔水凝胶。本发明还涉及大孔水凝胶，其能够通过本发明方法获得。该大孔水凝胶由交联聚合物组成，交联聚合物是聚乙二醇(PEG)或聚噁唑啉(POx)的衍生物。所述水凝胶展现出尺寸为200nm至1000μm、特别是500nm至100μm的互连大孔，并且特征在于pH是7.0至8.0，特别是约7.4。
