CN113226294 KIT FOR INHALED CHEMOTHERAPY, AND TREATMENT OF LUNG CANCER WITH SAID KIT

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Application Number 201980086586.9

Application Date 27.12.2019

Publication Number 113226294

Publication Date 06.08.2021

Publication Kind A

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Applicants VRIJE UNIVERSITEIT BRUSSEL
布鲁塞尔自由大学

Inventors AMIGHI KARIM
卡里姆·阿米吉
WAUTHOZ NATHALIE
纳塔莉·沃索兹
ROSIERE REMI
雷米·罗西埃

Agents 上海弼兴律师事务所 31283
上海弼兴律师事务所 31283

Priority Data PCT/EP2018/097140 28.12.2018 EP

Title

(EN) KIT FOR INHALED CHEMOTHERAPY, AND TREATMENT OF LUNG CANCER WITH SAID KIT

(ZH) 用于吸入式化学疗法的药盒以及使用所述药盒治疗肺癌

Abstract

(EN) Kit for an inhaled chemotherapy comprising a series of single hermetically packaged therapeutic doses of a dry powder for inhalation containing at least one anti-neoplastic agent chosen in the group consisting of platinum drugs with a lipid matrix and a PEGylated excipient and a series of disposable dry powder inhaler devices, its use and method of treatment of cancer lungs with said kit.

(ZH) 一种用于吸入式化学疗法的药盒、该药盒的用途以及使用所述药盒治疗癌肺的方法，该药盒包括一系列密封包装的单次治疗剂量的吸入用干粉以及一系列一次性干粉吸入器装置，该吸入用干粉包含至少一种抗肿瘤剂与脂质基质和聚乙二醇化赋形剂，该至少一种抗肿瘤剂选自由铂类药物组成的组。

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
72	for smoking or inhaling

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33	Medicinal preparations containing inorganic active ingredients
24	Heavy metals; Compounds thereof
243	Platinum; Compounds thereof

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
555	containing heavy metals, e.g. hemin, hematin, melarsoprol

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06	Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
26	Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

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1. CN113226294 - KIT FOR INHALED CHEMOTHERAPY, AND TREATMENT OF LUNG CANCER WITH SAID KIT

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
M	DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15	Inhalators

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
141	Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
148	with compounds of unknown constitution, e.g. material from plants or animals

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
141	Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
148	with compounds of unknown constitution, e.g. material from plants or animals