CN111838551 Flavonoid fermentation product, preparation method thereof and application thereof in blood glucose regulation

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Application Number 202010631726.0

Application Date 03.07.2020

Publication Number 111838551

Publication Date 30.10.2020

Publication Kind A

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Applicants JINAN RUILONGAN BIOTECHNOLOGY CO., LTD.
济南瑞隆安生物技术有限公司
SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
山东省药学科学院

Inventors LIU FEI
刘飞
WANG RUI
王锐
CHEN MIAN
陈勉
MA WENJING
马文靖
YUAN DANDAN
袁丹丹
ZHENG YAJUN
郑亚军
CHEN LEI
陈磊
LI QIAN
李倩
ZHANG XIAOYUAN
张晓元
ZHANG YANYAN
张艳艳

Agents 济南圣达知识产权代理有限公司 37221

Title

(EN) Flavonoid fermentation product, preparation method thereof and application thereof in blood glucose regulation

(ZH) 一种黄酮发酵物及其制备方法和在血糖调节中的应用

Abstract

(EN) The invention provides a flavonoid fermentation product and a preparation method and an application thereof in blood glucose regulation, and relates to the technical field of medicines. The fermentation method comprises the following steps: inoculating Lactobacillus bulgaricus and Streptococcus thermophilus into sterilized beancurd skin, carrying out first-order static fermentation, inoculating Kluyveromyces marxianus, aerating, and stirring to carry out second-order fermentation. According to the method, the raw materials are low in price and easy to obtain, the process steps are few, and theobtained fermented product, soybean protein, collagen peptide and soluble dietary fiber are prepared into the composition according to a specific proportion, so that the composition has a good fasting blood glucose reducing effect.

(ZH) 本发明提供一种黄酮发酵物及其制备方法和在血糖调节中的应用，涉及医药技术领域。所述发酵方法包括：在灭菌豆皮中接种保加利亚乳杆菌和嗜热链球菌进行一阶静态发酵，然后接种马克思克鲁维酵母通气搅拌进行二阶发酵。本发明的方法原料价格低廉易得，工艺步骤少，获得的发酵物与大豆蛋白、胶原肽和可溶性膳食纤维以特定比例制备成组合物后具有较好的降空腹血糖功效。

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
11	Pulses, i.e. fruits of leguminous plants, for production of fodder or food; Products from legumes; Preparation or treatment thereof, e.g. treatment with phosphates

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33	Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10	using additives
17	Amino acids, peptides or proteins
18	Peptides; Protein hydrolysates

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33	Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10	using additives
17	Amino acids, peptides or proteins
185	Vegetable proteins

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33	Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
20	Reducing nutritive value; Dietetic products with reduced nutritive value
21	Addition of substantially indigestible substances, e.g. dietary fibres

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36	Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18	Magnoliophyta (angiosperms)
185	Magnoliopsida (dicotyledons)
48	Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae

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1. CN111838551 - Flavonoid fermentation product, preparation method thereof and application thereof in blood glucose regulation

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
08	for glucose homeostasis
10	for hyperglycaemia, e.g. antidiabetics

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33	Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10	using additives
17	Amino acids, peptides or proteins
18	Peptides; Protein hydrolysates

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
V	INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002	Food compositions, function of food ingredients or processes for food or foodstuffs

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
Y	INDEXING SCHEME RELATING TO LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
2220	Lactobacillus
29	Delbrueckii