CN109793728 METHODS OF TREATING PANCREATIC CANCER

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Application Number 201910067315.0

Application Date 10.01.2014

Publication Number 109793728

Publication Date 24.05.2019

Publication Kind A

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Applicants ABRAXIS BIOSCIENCE LLC
阿布拉科斯生物科学有限公司

Inventors DESAI NEIL P
N·P·德赛
RENSCHLER MARKUS
M·雷恩施乐

Agents 北京纪凯知识产权代理有限公司 11245
北京纪凯知识产权代理有限公司 11245

Priority Data 13794480 11.03.2013 US
61/751,820 11.01.2013 US
61/752,355 14.01.2013 US

Title

(EN) METHODS OF TREATING PANCREATIC CANCER

(ZH) 治疗胰腺癌的方法

Abstract

(EN) Provided herein are methods for the treatment of metastatic pancreatic cancer comprising administration of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and a carrierprotein in combination with gemcitabine.

(ZH) 本发明的发明名称为治疗胰腺癌的方法。本文提供的是用于治疗转移性胰腺癌的方法，包括联合吉西他滨施用包括纳米颗粒的组合物，所述纳米颗粒包括紫衫烷(比如太平洋紫杉醇)和载体蛋白。

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
337	having four-membered rings, e.g. taxol

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30	Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42	Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7068	having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

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1. CN109793728 - METHODS OF TREATING PANCREATIC CANCER

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin