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1. CN109596595 - Application of semiconductor compound in benzaldehyde specificity detection, and benzaldehyde specificity detection method

Office China
Application Number 201811488385.5
Application Date 06.12.2018
Publication Number 109596595
Publication Date 09.04.2019
Publication Kind A
IPC
G01N 21/65
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
65Raman scattering
CPC
G01N 21/658
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
65Raman scattering
658enhancement Raman, e.g. surface plasmons
Applicants SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS, CHINESE ACADEMY OF SCIENCES
中国科学院苏州纳米技术与纳米仿生研究所
Inventors ZHAO ZHIGANG
赵志刚
PAN TING
潘婷
CONG SHAN
丛杉
Agents 南京利丰知识产权代理事务所(特殊普通合伙) 32256
南京利丰知识产权代理事务所(特殊普通合伙) 32256
Title
(EN) Application of semiconductor compound in benzaldehyde specificity detection, and benzaldehyde specificity detection method
(ZH) 半导体化合物在苯甲醛特异性检测中的应用及检测方法
Abstract
(EN)
The invention discloses application of a semiconductor compound in benzaldehyde specificity detection, and a benzaldehyde specificity detection method. The detection method comprises the following steps that: using the semiconductor compound as a SERS (Surface-Enhanced Raman spectroscopy) active substrate material, and enabling the semiconductor compound to be in contact with a detection sample which may contain benzaldehyde; then, carrying out detection by a Raman spectrometer; and according to a specificity Raman enhancement effect generated between the semiconductor compound and the benzaldehyde, realizing the benzaldehyde specificity detection. Compared with a noble metal substrate material, the detection method takes the semiconductor compound as the SERS active substrate material soas to exhibit the advantages of being wide in selectable range, low in cost, simple in operation, quick and effective. The semiconductor compound can generate the specificity Raman enhancement effecton the benzaldehyde, can realize the benzaldehyde specificity detection and can effectively distinguish benzyl alcohol from the benzaldehyde. A tiny quantity of benzaldehyde mixed in the common organic solvent benzyl alcohol of injection type medicines can be effectively identified, and the use safety of medicines can be guaranteed to a certain degree.

(ZH)
本发明公开一种半导体化合物在苯甲醛特异性检测中的应用及检测方法。所述检测方法包括:使用半导体化合物作为SERS活性基底材料,使其与可能含有苯甲醛的检测样品接触,之后以拉曼光谱仪进行检测,根据半导体化合物与苯甲醛之间产生特异性拉曼增强效果,实现苯甲醛的特异性检测。与贵金属基底材料相比,本发明以半导体化合物作为SERS活性基底材料,可选择范围广,成本低,操作简单,快速有效,半导体化合物可以对苯甲醛产生特异性拉曼增强效果,能够实现对苯甲醛的特异性检测,可有效区分苯甲醇、苯甲醛;本发明还能够有效识别检测出注射类药物常用有机溶剂苯甲醇中混有的微量苯甲醛,可在一定程度上保证药品使用的安全性。

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