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1. (CN109414457) TRANSPLANTATION MEDIUM

Office : China
Application Number: 201780041090.0 Application Date: 29.06.2017
Publication Number: 109414457 Publication Date: 01.03.2019
Publication Kind : A
Prior PCT appl.: Application Number:PCTJP2017023878 ; Publication Number: Click to see the data
IPC:
A61K 35/30
A61K 47/02
A61K 47/10
A61K 47/42
A61L 27/00
A61P 27/02
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
30
Nerves; Brain
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
Applicants: HEALIOS K K
希里欧斯株式会社
SUMITOMO DAINIPPON PHARMA CO., LTD.
大日本住友制药株式会社
Inventors: OTAGIRI DAI
小田切大
MAEDA TADAO
前田忠郎
Agents: 中科专利商标代理有限责任公司 11021
Priority Data: 2016-131171 30.06.2016 JP
Title: (EN) TRANSPLANTATION MEDIUM
(ZH) 移植用介质
Abstract: front page image
(EN) According to the present invention wherein RPE cells are suspended in a medium that contains poloxamer and is pharmaceutically acceptable as an eye perfusion/washing liquid, the survival ratio of theRPE cells having been freeze-preserved and then thawed can be increased, the visual cell-protecting effect of the RPE cells transplanted immediately after thawing can be improved, and a loss in the RPE cells in steps from thawing to transplantation can be avoided.
(ZH) 根据本发明,通过在含有泊洛沙姆的医药上容许用作眼内灌注液或清洗液的介质中悬浮RPE细胞,可以实现:提高冷冻保存了的RPE细胞解冻后的生存率、改善在刚刚解冻后移植时的由RPE细胞带来的视细胞保护效果、防止从解冻至移植的各种工序中的RPE细胞的损失。
Also published as:
AU2017287997CA3028613KR1020190026800EP3479832WO/2018/003908