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1. (CN108779433) Use of bacterial strains belonging to the species lactobacillus kefiri in paediatrics to generate and/or mantai n a state of homeostasis

Office : China
Application Number: 201780010531.0 Application Date: 09.02.2017
Publication Number: 108779433 Publication Date: 09.11.2018
Publication Kind : A
Prior PCT appl.: Application Number:PCTIB2017050713 ; Publication Number: Click to see the data
IPC:
C12N 1/20
A61K 35/747
A23L 33/135
C12R 1/225
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
[IPC code unknown for A61K 35/747][IPC code unknown for A23L 33/135]
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
R
INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1
Micro-organisms
01
Bacteria or actinomycetales
225
Lactobacillus
CPC:
A61K 35/747
A23L 33/115
A23L 33/135
A23V 2002/00
A23Y 2220/47
A61K 9/145
A61K 9/5015
A61K 47/14
A61K 47/44
A61K 2035/115
C12N 1/20
C12R 1/225
Applicants: PROBIOTICAL SPA
波比奥泰克股份公司
HULKA S R L
胡尔卡公司
Inventors: MOGNA GIOVANNI
G·莫格纳
Agents: 北京三友知识产权代理有限公司 11127
北京三友知识产权代理有限公司 11127
Priority Data: 102016000014907 12.02.2016 IT
102016000048058 10.05.2016 IT
Title: (EN) Use of bacterial strains belonging to the species lactobacillus kefiri in paediatrics to generate and/or mantai n a state of homeostasis
(ZH) 属于开菲尔乳杆菌种的细菌菌株在用于产生和/或维持体内稳态状态的儿科学中的应用
Abstract: front page image
(EN) The present invention relates to the use of bacterial strains belonging to the species Lactobacillus kefiri in paediatrics to generate and/or maintain the state of homeostasis. The present invention further relates to bacterial strains belonging to the species Lactobacillus kefiri having a high capacity to adhere to the intestinal epithelium; in particular, the present invention relates to the bacterial strains Lactobacillus kefiri LKF01 DSM 32079 LKEF and Lactobacillus kefiri LKF02 DSM 32080 for use in paediatrics. Finally, the present invention relates to a food composition, or a compositionfor a supplement, or a composition for a medical device, or a pharmaceutical composition (briefly all together the composition(s) of the present invention) comprising excipients and/or substances ofa food or pharmaceutical grade formulation, and a mixture which comprises or, alternatively, consists of a bacterial strain selected from the group consisting of the bacterial strains belonging to thespecies Lactobacillus kefiri, said composition being for use in paediatrics to generate and/or maintain the state of homeostasis and for use in the preventive and/or curative treatment of inflammatory intestinal diseases, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis (UC), in adult subjects, also in a chronic stage.
(ZH) 本发明涉及属于开菲尔乳杆菌(Lactobacillus kefiri)种的细菌菌株在用于产生和/或维持体内稳态状态的儿科学中的应用。本发明还涉及具有较高的粘附于小肠上皮的能力的属于开菲尔乳杆菌种的细菌菌株;特别是,本发明涉及用于儿科学的细菌菌株开菲尔乳杆菌LKF01 DSM 32079 LKEF和开菲尔乳杆菌LKF02 DSM 32080。最后,本发明涉及食物组合物、或用于补充的组合物、或用于医疗器械的组合物、或药物组合物(简言之总称为本发明的组合物),其包含赋形剂和/或食品或药品级制剂的物质以及包含选自由属于开菲尔乳杆菌种的细菌菌株组成的组的细菌菌株的混合物或由细菌菌株组成的混合物;所述组合物应用于儿科学中以产生或维持体内稳态状态以及用于对成年受试者中而且处于慢性期的如肠易激综合征(IBS)、炎性肠病(IBD)、克罗恩病和溃疡性结肠炎(UC)等炎性肠疾病的预防性和/或疗愈性治疗。
Also published as:
AU2017217350CA3013280EP3414317BR112018016458US20190038682WO/2017/137920