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1. CN108079290 - Novel vaccine compositions comprising immunostimulatory oligonucleotides

Office
China
Application Number 201810130911.4
Application Date 12.05.2014
Publication Number 108079290
Publication Date 29.05.2018
Publication Kind A
IPC
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
A61P 33/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
33Antiparasitic agents
02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
A61P 31/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
22for herpes viruses
CPC
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61K 39/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
27Equine rhinopneumonitis virus
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 2039/55561
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55561CpG containing adjuvants; Oligonucleotide containing adjuvants
A61K 2039/55566
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55566Emulsions, e.g. Freund's adjuvant, MF59
Applicants ZOETIS SERVICES LLC
硕腾服务有限责任公司
Inventors DOMINOWSKI PAUL JOSEPH
P·J·多明诺夫斯基
RAI SHARATH K.
S·K·雷
SLY LAUREL MARY
L·M·斯莱
COOK COREY PATRICK
C·P·库克
MWANGI DUNCAN
D·姆旺吉
FOSS DENNIS L.
D·L·福斯
KREBS RICHARD LEE
R·L·克雷布斯
Agents 中国国际贸易促进委员会专利商标事务所 11038
Priority Data 61/823,189 14.05.2013 US
Title
(EN) Novel vaccine compositions comprising immunostimulatory oligonucleotides
(ZH) 包含免疫刺激性寡核苷酸的新颖疫苗组合物
Abstract
(EN) The invention provides a vaccine composition comprising an antigen component and an adjuvant component, wherein the adjuvant component comprises a P-class immunostimulatory oligonucleotide and eithera combination of a saponin and a sterol; or an oily phase comprising an oil and, optionally, one or more emulsifiers, said oily phase comprising 2-20% v/v of the vaccine composition, wherein said antigen component is an EHV antigen or a Leishmania antigen.
(ZH) 本发明提供了一种包含抗原组分和佐剂组分的疫苗组合物,其中所述佐剂组分包含P类免疫刺激性寡核苷酸以及皂苷与甾醇的组合;或包含油和任选的一种或多种乳化剂的油相,所述油相占所述疫苗组合物的2‑20%v/v,其中所述抗原组分是EHV抗原或利什曼虫抗原。