(EN) The present invention relates to a benzofuran derivative, a preparation method thereof and a use thereof in medicine. In particular, the present invention relates to the benzofuran derivative as shown by general formula (I), the preparation method thereof, a pharmaceutical composition containing the derivative, and uses thereof as an EZH2 inhibitor and in the prevention and/or treatment of diseases such as tumours and cancers, etc., and in particular uses thereof in the prevention and/or treatment of non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and synovial sarcoma, wherein the definitions of the substituents in the general formula (I) are the same as those defined in the description.
(ZH) 本发明涉及苯并呋喃类衍生物、其制备方法及其在医药上的应用。特别地,本发明涉及通式(I)所示的苯并呋喃类衍生物、其制备方法、含有该衍生物的药物组合物,以及其作为EZH2抑制剂以及其预防和/或治疗肿瘤和癌症等疾病的用途,特别是预防和/或治疗非霍奇金淋巴瘤、弥漫大B细胞淋巴瘤、滤泡性淋巴瘤、滑膜肉瘤的用途,其中通式(I)中的各取代基与说明书中的定义相同。