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1. (CN107299101) Non-coding immunomodulatory DNA construct

Office : China
Application Number: 201710516200.6 Application Date: 23.12.2011
Publication Number: 107299101 Publication Date: 27.10.2017
Publication Kind : A
IPC:
C12N 15/117
A61K 48/00
A61K 31/711
A61K 39/00
A61P 35/00
A61P 37/02
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
117
Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
711
Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
Applicants: MOLOGEN AG
Inventors: SCHROFF MATTHIAS
KLEUSS CHRISTIANE
KAPP KERSTIN
Priority Data: 1021867.5 23.12.2010 GB
Title: (EN) Non-coding immunomodulatory DNA construct
(ZH) 非编码免疫调节DNA 构建体
Abstract: front page image
(EN) The present invention relates to a nucleic acid molecule and its use for the modulation of the immune system. It provides a DNA construct for immunomodulation comprising at least one nucleotide in L-conformation.
(ZH) 本发明涉及核酸分子及其在调节免疫系统中的用途。提供了用于免疫调节的DNA构建体,其包含至少一个L‑构象的核苷酸。
Also published as:
CA2822377EP2655623US20140010830JP2014504158SG191328MX343918
RU2013132151KR1020130126680RU0002583291KR1020160113332AU2011347095DK2655623
ES2618783ID2016/01789IL227105CN107384930IN6051/DELNP/2013BR112013015816
WO/2012/085291