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1. CN106414376 - Process for obtaining optically active pirlindole enantiomers and salts thereof

Office China
Application Number 112014000078731
Application Date 09.05.2014
Publication Number 106414376
Publication Date 15.02.2017
Grant Number 106414376
Grant Date 07.06.2019
Publication Kind B
IPC
C07B 57/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
57Separation of optically-active organic compounds
C07D 487/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
06Peri-condensed systems
CPC
C07B 57/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
57Separation of optically-active compounds
C07D 487/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
06Peri-condensed systems
C07B 2200/07
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
07Optical isomers
A61K 31/495
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants TECNIMEDE SOCIEDADE TECNICO-MEDICINAL S.A.
特克尼梅德医疗技术股份公司
Inventors PARDAL FILIPE AUGUSTO EUGENIO
奥古斯托·欧根尼奥·帕达尔·菲利佩
EUFRASIO PEDROSO PEDRO FILIPE
佩德罗·菲利佩·欧弗拉西奥·佩德罗索
ALMEIDA PECORELLI SUSANA MARQUES
苏珊娜·马奎斯·阿尔梅达·佩克雷利
CASIMIRO CAIXADO CARLOS ALBERTO EUFRASIO
卡洛斯·阿尔贝托·欧弗拉西奥·卡西米罗·采夏多
LOPES ANA SOFIA DA CONCEICAO
安娜·索非亚·达·康西卡奥·洛佩斯
DAMIL JOAO CARLOS RAMOS
若奥·卡洛斯·拉莫斯·戴米尔
E OLIVEIRA SANTOS PEDRO PAULO DE LACERDA
佩德罗·保罗·德拉塞达·译奥利维拉·圣多斯
Agents 北京市万慧达律师事务所 11111
北京市万慧达律师事务所 11111
Title
(EN) Process for obtaining optically active pirlindole enantiomers and salts thereof
(ZH) 获得光学活性吡吲哚对映异构体及其盐的方法
Abstract
(EN)
The present invention provides a new process for obtaining optically active pirlindole enantiomers, in the form of a free base or in the form of pharmaceutically acceptable salts. The products obtained according to the present invention are enantiomerically pure and are useful in medicine.

(ZH)
本发明提供一种获得光学活性吡吲哚对映异构体的新方法,其处于游离碱的形式或者处于药学上可接受的盐的形式。本发明所获得的产物是对映异构体纯的,并且可用作药物。

Also published as
CL2016-2843
CONC2016/0003926
GE14340
GE14340/1
IR139550140003010460
KZ2016/1150.1
MA39449
SA516380265
UAa201611334