(EN) Disclosed are a novel crystal form of Dabrafenib mesylate and preparation method thereof. The novel crystal form of the present invention is more stable in water or an aqueous system, and has greater solubility and dissolution in water, thus having better stability and bioavailability compared with the existing crystal forms.
(ZH) 本发明涉及达拉菲尼甲磺酸盐的新晶型及其制备方法。本发明所述新晶型具有在水或含水体系中更稳定和水中溶解度、溶出量更大的优点,因此相对于现有的晶型,具有更好的稳定性和生物利用度。