CN104169268 三环砜化合物及其制备和使用方法

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Application Number 201380014172.8

Application Date 17.01.2013

Publication Number 104169268

Publication Date 26.11.2014

Publication Kind A

IPC

CPC

Applicants 扎夫根股份有限公司

Inventors T·D·帕林
H·J·戴克
S·M·克兰普
R·赞勒

Agents 中国国际贸易促进委员会专利商标事务所 11038

Priority Data 61/587,825 18.01.2012 US

Title

(ZH) 三环砜化合物及其制备和使用方法

Abstract

(ZH)

本发明提供三环砜化合物和它们在治疗医学病症如肥胖症中的用途。提供了药物组合物和制备各种三环化合物的方法。预期所述化合物对甲硫氨酰氨基肽酶2具有活性。

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
311	Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02	ortho- or peri-condensed with carbocyclic rings or ring systems
78	Ring systems having three or more relevant rings

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
35	having six-membered rings with one oxygen as the only ring hetero atom
352	condensed with carbocyclic rings, e.g. cannabinols, methantheline
353	3,4-Dihydrobenzopyrans, e.g. chroman, catechin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
04	Anorexiants; Antiobesity agents

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
311	Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02	ortho- or peri-condensed with carbocyclic rings or ring systems
78	Ring systems having three or more relevant rings

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
35	having six-membered rings with one oxygen as the only ring hetero atom
352	condensed with carbocyclic rings, e.g. cannabinols, methantheline
353	3,4-Dihydrobenzopyrans, e.g. chroman, catechin