CL2018000893 HETERODÍMEROS E1/E2 DEL VIRUS DE LA HEPATITIS C Y MÉTODOS PARA PRODUCIRLOS

La presente descripción proporciona polipéptidos heterodiméricos con etiqueta de afinidad que comprenden un polipéptido E1 del virus de la hepatitis C (VHC) y un polipéptido E2 de VHC, en donde uno o ambos polipéptidos E1 y E2 comprenden una etiqueta de afinidad. La presente descripción proporciona un método para producir un heterodímero E1/E2 con etiqueta de afinidad de la presente descripción. La presente descripción proporciona métodos para producir heterodímeros E1/E2 de VHC sin etiquetas

Also published as

AU2016336150

CN108290960

EP3359577

US20180282377

WO/2017/060857

JP2018533934

CA3000313

IN201817011822

CL2018-893

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31	Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12	Antivirals
14	for RNA viruses

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39	Medicinal preparations containing antigens or antibodies
385	Haptens or antigens, bound to carriers

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37	Drugs for immunological or allergic disorders
02	Immunomodulators
04	Immunostimulants

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
1	General processes for the preparation of peptides
14	Extraction; Separation; Purification
16	by chromatography
22	Affinity chromatography or related techniques based upon selective absorption processes

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
14	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005	from viruses
08	RNA viruses
18	Togaviridae, e.g. flavivirus, pestivirus, yellow fever virus, hepatitis C virus, japanese encephalitis virus

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1. CL2018000893 - HETERODÍMEROS E1/E2 DEL VIRUS DE LA HEPATITIS C Y MÉTODOS PARA PRODUCIRLOS

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C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
11	DNA or RNA fragments; Modified forms thereof
31	Genes encoding microbial proteins, e.g. enterotoxins
33	Genes encoding viral proteins
51	Hepatitis viruses

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21	Preparation of peptides or proteins
02	having a known sequence of two or more amino acids, e.g. glutathione

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
2319	Fusion polypeptide
30	Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto