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1. CA2189970 - MATRIX SYSTEM FOR THE TRANSDERMAL DELIVERY OF IBUPROFEN, AND METHOD FOR PREPARING SAME

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Canada
Application Number 2189970
Application Date 10.05.1995
Publication Number 2189970
Publication Date 23.11.1995
Publication Kind A1
IPC
A61K 31/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
A61K 9/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
A61K 47/32
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
CPC
A61K 9/7061
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
7053obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
7061Polyacrylates
A61K 31/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
Applicants LABORATOIRES D'HYGIENE ET DE DIETETIQUE (L.H.D.)
Inventors SAWAYA, ANTOINE
MATH, MARIE-CHRISTINE
Priority Data 9405818 11.05.1994 FR
Title
(EN) MATRIX SYSTEM FOR THE TRANSDERMAL DELIVERY OF IBUPROFEN, AND METHOD FOR PREPARING SAME
(FR) SYSTEME MATRICIEL POUR ADMINISTRATION TRANSDERMIQUE D'IBUPROFENE ET PROCEDE DE PREPARATION
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Abstract
(EN) The invention relates to a self-adhesive transdermal matrix system for the transdermal delivery of ibuprofen, in which matrix system, which comprises acarrier and a self-adhesive matrix, said matrix includes: (a) 55 to 75 parts by weight of an adhesive acrylate copolymer with a glass transition temperature of between -70 and -10°C, (b) 5 to 15 parts by weight of a cationic acrylate copolymer with a glass transition temperature of between 20 and 80°C, (c) 5 to 15 parts by weight of ibuprofen in the form of the free acid, and (d) 10 to 25 parts by weight of diethyl phthalate. It further relates to a method of preparing such a matrix system.
Related patent documents
FR2719770
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NO19964743This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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