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1. (CA2045621) PHYSIOLOGICALLY ACTIVE SUBSTANCE BE-16627

Office : Canada
Application Number: 2045621 Application Date: 20.11.1990
Publication Number: 2045621 Publication Date: 25.05.1991
Publication Kind : A1
Prior PCT appl.: Application Number:JP1990001509 ; Publication Number: Click to see the data
IPC:
C12P 21/02
A61K 38/05
C07K 5/06
C07K 5/062
C12N 1/20
A61K 38/00
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
02
having a known sequence of two or more amino acids, e.g. glutathione
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
05
Dipeptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
06
Dipeptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
06
Dipeptides
062
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
CPC:
C12R 1/465
A61K 38/00
C07K 5/06069
Applicants:
Inventors: OKUYAMA, AKIRA
KANBAYASHI, NOBUO
NAITO, KYOZO
SUZUKI, HAJIME
NAKAJIMA, SHIGERU
SUDA, HIROYUKI
OKANISHI, MASANORI
Priority Data: 01-305764 24.11.1989 JP
Title: (EN) PHYSIOLOGICALLY ACTIVE SUBSTANCE BE-16627
(FR) SUBSTANCE BE-16627 ACTIVE PHYSIOLOGIQUEMENT
Abstract: front page image
(EN) ABSTRACT The present invention relates to new stromelysin (human) - inhibitors, i.e., physiologically active substances BE-16627 represented by the general formula: [I] wherein R represents a hydrogen atom or a methyl group, or pharmaceutically acceptable salts thereof, a process for the production and use thereof, and a microorganism producing the substance BE-16627.


Also published as:
EP0455818WO/1991/008222