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1. (CA2778442) METHODS AND COMPOSITIONS FOR MODULATING HEPSIN ACTIVATION OF MACROPHAGE-STIMULATING PROTEIN

Office : Canada
Application Number: 2778442 Application Date: 21.10.2010
Publication Number: 2778442 Publication Date: 28.04.2011
Publication Kind : A1
Prior PCT appl.: Application Number:US2010053600 ; Publication Number: Click to see the data
IPC:
A61K 39/395
C12Q 1/37
G01N 33/53
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
34
involving hydrolase
37
involving peptidase or proteinase
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
CPC:
C07K 16/40
A61K2039/505
C07K2317/76
G01N 33/68
G01N2333/705
G01N2333/96433
G01N2500/02
Applicants: GENENTECH, INC.
Inventors: GANESAN, RAJKUMAR
KIRCHHOFER, DANIEL
Priority Data: 61/253,990 22.10.2009 US
Title: (EN) METHODS AND COMPOSITIONS FOR MODULATING HEPSIN ACTIVATION OF MACROPHAGE-STIMULATING PROTEIN
(FR) PROCEDES ET COMPOSITIONS POUR MODULER L'ACTIVATION D'HEPSINE D'UNE PROTEINE DE STIMULATION DE MACROPHAGE
Abstract:
(EN) The invention provides methods and compositions for modulating hepsin activity and the MSP/Ron pathway, in particular by regulating pro-MSP activation by hepsin.


Also published as:
EP2490718US20120282271JP2013507967CN102711826RU2012120863MX2012004617
RU0002539772KR1020120105446ES2564207BR112012009409IN3566/CHENP/2012WO/2011/050194