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1. (CA2747251) METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTIONS AND ASSOCIATED DISORDERS

Office : Canada
Application Number: 2747251 Application Date: 26.01.2010
Publication Number: 2747251 Publication Date: 29.07.2010
Publication Kind : A1
Prior PCT appl.: Application Number:US2010022112 ; Publication Number: Click to see the data
IPC:
A61K 31/4418
A61P 9/10
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4418
having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
CPC:
A61K 31/415
A61K 31/00
A61K 31/4365
A61K 31/437
A61K 31/4418
A61K 31/4433
A61K 31/4436
A61K 31/4439
A61K 31/444
A61K 31/496
A61K 31/4965
A61K 31/50
A61K 31/506
A61K 31/513
A61K 31/53
A61K 31/5377
A61K 31/706
Applicants: INTERMUNE, INC.
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: OLGIN, JEFF
KOSSEN, KARL
Priority Data: 61/147,340 26.01.2009 US
Title: (EN) METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTIONS AND ASSOCIATED DISORDERS
(FR) METHODES DE TRAITEMENT D'INFARCTUS DU MYOCARDE AIGUS ET TROUBLES ASSOCIES
Abstract:
(EN) The invention relates to methods of treating patients who have suffered an acute myocardial infarction (AMI) with a therapeutic that has anti-fibrotic effects, for example, pirfenidone and analogs thereof The method of treating a patient who has suffered an acute myocardial infarction may include administering to the patient a therapeutically effective dose of a therapeutic having an anti-fibrotic effect, wherein optionally the treatment is initiated at a time period about 1 to 42 days after suffering the AMI, and optionally continues for up to 3 to 6 months


Also published as:
NZ593583UAa201109441IL213526MXMX/a/2011/007854SG172981EP2389227
JP2012515800CN102292124MX2011007854KR1020110114684TN2011000364BRPI1006979
AU2010206543ID2012/00475MYPI 2011003334IN5985/DELNP/2011WO/2010/085805