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1. CA2759891 - GPR 119 MODULATORS

Office Canada
Application Number 2759891
Application Date
Publication Number 2759891
Publication Date 11.11.2010
Publication Kind A1
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
08
Bridged systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
04
Anorexiants; Antiobesity agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
C07D 498/08
A61K 31/519
A61P 3/00
A61P 3/04
A61P 3/10
CPC
C07D 471/04
C07D 401/14
C07D 491/08
Applicants PFIZER INC.
Inventors DAROUT, ETZER
DENINNO, MICHAEL PAUL
FUTATSUGI, KENTARO
GUIMARAES, CRISTIANO RUCH WERNECK
LEFKER, BRUCE ALLEN
MASCITTI, VINCENT
MCCLURE, KIM FRANCIS
MUNCHHOF, MICHAEL JOHN
ROBINSON, RALPH PELTON, JR.
Priority Data 61/176,528 08.05.2009 US
61/320,462 02.04.2010 US
Title
(EN) GPR 119 MODULATORS
(FR) MODULATEURS DU GPR119
Abstract
(EN)
Compounds of Formula (I) that modulate the activity of the G -protein-coupled receptor GPFM 19 and their uses in the treatment of diseases linked to the modulation of the G-protein-coupled receptor GPR119 in animals are described herein.