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1. CA2638828 - IMMUNOMODULATORY AND ANTI-TUMOR PEPTIDES DERIVED FROM LALF

Office
Canada
Application Number 2638828
Application Date
Publication Number 2638828
Publication Date 30.08.2007
Grant Number
Grant Date 09.09.2014
Publication Kind C
IPC
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
A61P 37/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
04Immunostimulants
C07K 14/43509
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
43504from invertebrates
43509from crustaceans
Applicants CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
Priority Data 20060047 24.02.2006 CU
Title
(EN) IMMUNOMODULATORY AND ANTI-TUMOR PEPTIDES DERIVED FROM LALF
(FR) PEPTIDES IMMUNOMODULATEURS ET ANTITUMEURS ISSUS DE LA PROTEINE LIMULUS ANTILIPOPOLYSACCHARIDE
Abstract
(EN)


The present invention is related to the development of peptides derived from
the
sequence HYRIKPTFRRLKWKKYKGKFW, showing aminoacids substitutions,
these peptides unable to bind to the lipopolysaccharide and bearing anti-
tumoral
and immunomodulatory capacities. These peptides alone or in combination are
useful to treat cancer, and also in synergy with conventional therapies.