CA2599734 HUMANIZED L243 ANTIBODIES

Humanized antibodies are provided that specifically bind HLA-DR. The
antibodies recognize the epitope recognized by the murine monoclonal antibody
L243. Processes for preparing such antibodies, pharmaceutical compositions
containing such antibodies, and clinical therapuetic and diagnostic, as well
as research-related uses for such antibodies, are provided.

Also published as

AU2006218454

AU2011253938

BRPI0607486

CN101171034

CN103936859

DK3332808

EP1853313

EP3332808

ES2665422

IN201618040221

IN7066/DELNP/2007

JP2008532949

MXMX/a/2007/010672

WO/2006/094192

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
16	Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46	Hybrid immunoglobulins

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50	the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51	the non-active ingredient being a modifying agent
68	the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39	Medicinal preparations containing antigens or antibodies
395	Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49	Preparations for testing in vivo

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51	Preparations containing radioactive substances for use in therapy or testing in vivo
02	characterised by the carrier
04	Organic compounds
08	Peptides, e.g. proteins
10	Antibodies or immunoglobulins; Fragments thereof

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1. CA2599734 - HUMANIZED L243 ANTIBODIES

WIPO Translate

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
16	Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18	against material from animals or humans
28	against receptors, cell surface antigens or cell surface determinants

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
14	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435	from animals; from humans
705	Receptors; Cell surface antigens; Cell surface determinants
74	Major histocompatibility complex (MHC)

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25	Drugs for disorders of the nervous system
28	for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
16	Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18	against material from animals or humans
28	against receptors, cell surface antigens or cell surface determinants
2803	against the immunoglobulin superfamily
2833	against MHC-molecules, e.g. HLA-molecules