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1. (CA2072620) URINARY TUMOR ASSOCIATED ANTIGEN, ANTIGENIC SUBUNITS USES AND METHODS OF DETECTION

Office : Canada
Application Number: 2072620 Application Date: 31.10.1990
Publication Number: 2072620 Publication Date: 16.05.1991
Grant Number: Grant Date: 12.06.2007
Publication Kind : C
Prior PCT appl.: Application Number:US1990006339 ; Publication Number: Click to see the data
IPC:
C12P 21/08
A61K 39/00
A61K 39/395
A61K 47/48
A61K 49/00
C07K 14/47
C07K 16/30
C07K 16/42
G01N 33/574
G01N 33/577
A61K 38/00
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
08
Monoclonal antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
30
from tumour cells
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
42
against immunoglobulins (anti-idiotypic antibodies)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
577
involving monoclonal antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
CPC:
G01N 33/57484
A61K 38/00
A61K 39/00
A61K 47/6851
A61K 47/6873
A61K 49/00
C07K 14/4748
C07K 16/30
C07K 16/4266
C07K 2317/734
G01N 33/57407
Y10S 530/828
Applicants: MORTON, DONALD L.
Inventors: MORTON, DONALD L.
Priority Data: 431,533 03.11.1989 US
Title: (EN) URINARY TUMOR ASSOCIATED ANTIGEN, ANTIGENIC SUBUNITS USES AND METHODS OF DETECTION
(FR) ANTIGENE LIE A UNE TUMEUR URINAIRE, UTILISATIONS DE SOUS-UNITES ANTIGENIQUES ET METHODES DE DETECTION
Abstract: front page image
(EN) The invention provides a substantially purified antigenic polypeptide of urinary tumor associated antigen having, after reuction by beta-mercaptoethanol and separation by SDS-polyacrylamide gel electrophoresis, a molecular weight of about 90 to 100 kD. Monoclonal antibodies, methods of detecting cancers, methods of immunotherapy, methods for monitoring a malignan- cy, a method of detecting urinary tumor associated antigen, tumor cell vaccines or polypeptide vaccine and other methods relat- ing to urinary tumor associated antigen are also provided.


Also published as:
EP0498851EP0678744ES2084715JP3423306JPH05505596JP2001281255
CA2331088DE000069024659DE000069033295AU1991068753DK0498851WO/1991/006866