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1. CA2509035 - CONTRAST MEDIA FORMULATIONS HAVING IMPROVED BIOLOGICAL TOLERANCE

Office
Canada
Application Number 2509035
Application Date 07.11.2003
Publication Number 2509035
Publication Date 01.07.2004
Grant Number
Grant Date 19.07.2011
Publication Kind C
IPC
A61K 49/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
CPC
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61K 49/0433
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
0433containing an organic halogenated X-ray contrast-enhancing agent
A61K 49/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
A61K 49/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
Applicants BIOPHYSICA, INC.
Inventors SOVAK, MILOS
SELIGSON, ALLEN L.
TERRY, RONALD C.
Priority Data 10701586 05.11.2003 US
60/432,879 12.12.2002 US
Title
(EN) CONTRAST MEDIA FORMULATIONS HAVING IMPROVED BIOLOGICAL TOLERANCE
(FR) FORMULATIONS DE MILIEU DE CONTRASTE PRESENTANT UNE TOLERANCE BIOLOGIQUE AMELIOREE
Abstract
(EN) This invention comprises new formulations of radiographic contrast media including dimeric non-ionic media, with an organic amine and a carboxylic acid. Formulations of this invention increase the biological tolerance of such media, thereby increasing their safety.