Processing

Please wait...

Settings

Settings

Goto Application

1. CA2220403 - METHOD FOR PREPARING ENANTIOMERIC FORMS OF AMINO ALKYLAMINOPHENYL PROPANOIC ACID

Office Canada
Application Number 2220403
Application Date 10.06.1996
Publication Number 2220403
Publication Date 27.12.1996
Publication Kind A1
IPC
C07C 229/42
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
40having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
42with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
C07C 227/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
227Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
14from compounds containing already amino and carboxyl groups or derivatives thereof
C07C 227/32
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
227Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
30Preparation of optical isomers
32by stereospecific synthesis
C07C 229/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
02having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
04the carbon skeleton being acyclic and saturated
06having only one amino and one carboxyl group bound to the carbon skeleton
10the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
12to carbon atoms of acyclic carbon skeletons
C07K 7/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
CPC
C07C 227/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
227Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
14from compounds containing already amino and carboxyl groups or derivatives thereof
C07C 229/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
02having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
04the carbon skeleton being acyclic and saturated
06having only one amino and one carboxyl group bound to the carbon skeleton
10the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
12to carbon atoms of acyclic carbon skeletons
Applicants RHONE-POULENC RORER S.A.
Inventors STAMMLER, ROBERT
Priority Data 95 06890 12.06.1995 FR
Title
(EN) METHOD FOR PREPARING ENANTIOMERIC FORMS OF AMINO ALKYLAMINOPHENYL PROPANOIC ACID
(FR) PROCEDE DE PREPARATION DES FORMES ENANTIOMERES DE L'ACIDE AMINO ALKYLAMINOPHENYL PROPANOIQUE
Abstract
(EN)

(FR)
Procédé de préparation d'une forme énantiomère de l'acide amino-2(alkylamino-4 phényl)-3 propanoïque de formule générale (I), dans laquelle Alk représente un radical alcoyle contenant 1 à 2 atomes de carbone, sous forme (S) ou (R), ainsi que de ses sels, à partir respectivement de la (L)-phénylalanine ou de la (D)-phénylalanine, par nitration, puis transformation du radical nitro de la nitro-4 phénylalanine obtenue, de formule générale (II), dans laquelle R est un atome d'hydrogène ou un radical protecteur, en un radical alcoylamino, après protection le cas échéant de la fonction amine de la phénylalanine.