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1. CA3150516 - DNA-PK INHIBITING COMPOUNDS

Office
Canada
Application Number 3150516
Application Date 11.09.2019
Publication Number 3150516
Publication Date 18.03.2021
Publication Kind A1
IPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/4375
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
4375the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
CPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 519/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
519Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applicants PROVINCIAL HEALTH SERVICES AUTHORITY
MINCHINTON, ANDREW IVOR
KYLE, ALASTAIR HUGH
EVANS, JAMES
MANN, SAMUEL EDWARD
HYND, GEORGE
Inventors MINCHINTON, ANDREW IVOR
KYLE, ALASTAIR HUGH
EVANS, JAMES
MANN, SAMUEL EDWARD
HYND, GEORGE
Title
(EN) DNA-PK INHIBITING COMPOUNDS
(FR) COMPOSES INHIBITEURS DE L'ADN-PK
Abstract
(EN) The present disclosure relates to DNA-PK inhibiting compounds and prodrugs thereof that are useful in the treatment of diseases, including cancer. In particular, the compounds sensitise cancers to therapies such as chemotherapy and radiotherapy.
(FR) La présente invention concerne des composés inhibiteurs d'ADN-PK et des promédicaments de ceux-ci qui sont utiles dans le traitement de maladies, y compris le cancer. En particulier, les composés sensibilisent les cancers à des thérapies telles que la chimiothérapie et la radiothérapie.
Related patent documents
EP2019773688This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.