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1. CA3013463 - HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF

Office Canada
Application Number 3013463
Application Date
Publication Number 3013463
Publication Date 10.08.2017
Publication Kind A1
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
A61K 39/395
C07K 16/28
C07K 16/46
C07K 19/00
C12N 15/13
CPC
A61K 47/6803
A61K 47/6849
A61K 47/6869
A61P 35/00
C07K 16/2803
C07K 2317/24
Applicants THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH
Priority Data 62/291,143 04.02.2016 US
Title
(EN) HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF
(FR) ANTICORPS HUMANISES ANTI-CD3, CONJUGUES ET LEURS UTILISATIONS
Abstract
(EN)
The present invention provides for humanized anti-CD3 antibodies and conjugates thereof. These conjugates may be useful in the treatment of conditions such as prostate cancer.