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1. CA3005961 - AN A3 ADENOSINE RECEPTOR LIGAND FOR USE IN TREATING ECTOPIC FAT ACCUMULATION

Office
Canada
Application Number 3005961
Application Date
Publication Number 3005961
Publication Date 01.06.2017
Publication Kind A1
IPC
A61K 31/7076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
CPC
A61K 31/7076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61K 9/0053
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
Applicants CAN-FITE BIOPHARMA LTD.
Priority Data 242723 23.11.2015 IL
Title
(EN) AN A3 ADENOSINE RECEPTOR LIGAND FOR USE IN TREATING ECTOPIC FAT ACCUMULATION
(FR) LIGAND DU RECEPTEUR DE L'ADENOSINE A3 POUR LE TRAITEMENT DE L'ACCUMULATION DE GRAISSE ECTOPIQUE
Abstract
(FR) La présente invention concerne le ligand du récepteur de l'adénosine A3 pour réduire l'accumulation de graisse ectopique, en particulier dans la stéatose hépatique. La présente invention concerne également l'utilisation du ligand du récepteur de l'adénosine A3 pour la préparation d'une composition pharmaceutique permettant de réduire l'accumulation de graisse, une méthode de traitement d'un état associé à l'accumulation de graisse utilisant le ligand et des trousses comprenant des compositions pharmaceutiques comprenant le ligand, et des instructions concernant leur utilisation, pour traiter un état associé à l'accumulation de graisse ectopique. Dans un mode de réalisation, la présente invention porte sur l'utilisation d'un agoniste du récepteur de l'adénosine A3, tel que le 2-chloro-N6-(3-iodobenzyl) -adénosine-5 '-N-méthyluronamide (C1-IB-MECA, CF102) pour le traitement de la stéatose hépatique, en particulier, la stéatose hépatique non alcoolique (NAFLD).


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RSP-2021/0079This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.