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1. (CA2948589) 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS

Office : Canada
Application Number: 2948589 Application Date:
Publication Number: 2948589 Publication Date: 26.11.2015
Publication Kind : A1
Prior PCT appl.: Application Number:PCTEP2015061350 ; Publication Number: Click to see the data
IPC:
C07D 487/04
A61K 31/519
A61P 11/06
A61P 29/00
C07D 519/00
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
519
Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/ or C07D455/257
CPC:
A61K 31/519
C07D 471/04
C07D 487/04
C07D 519/00
A61P 11/06
C07D 403/14
Applicants: F. HOFFMANN-LA ROCHE AG
Inventors:
Priority Data: PCT/CN2015/077176 22.04.2015 CN
62/002,547 23.05.2014 US
62/101,234 08.01.2015 US
62/130,098 09.03.2015 US
Title: (EN) 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS
(FR) COMPOSES 5-CHLORO -2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE UTILISES EN TANT QU'INHIBITEURS DE JAK
Abstract: front page image
(EN) Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein. Claimed uses are the treatment of inflammation and asthma.


Also published as:
SG11201609830RIL248661CN106459039EP3145929AU2015261812US20170145020
JP2017516850KR1020170005870PH1/2016/502099ID2017/12804IN201647039563EA201692338
MYPI 2016002027US20180305355CR20160539WO/2015/177326