BR112016023086 composto, composição, e, uso dos mesmos

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Brazil

Application Number 112016023086

Application Date 08.04.2015

Publication Number 112016023086

Publication Date 29.06.2021

Publication Kind A8

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CPC

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Applicants ABLIVA AB
NEUROVIVE PHARMACEUTICAL AB

Inventors ESKIL ELMÉR
KARL HENRIK JOHANNES EHINGER
MAGNUS JOAKIM HANSSON
STEVEN MOSS

Agents KASZNAR LEONARDOS PROPRIEDADE INTELECTUAL

Priority Data PA 2014 70190 08.04.2014 DK

Title

(PT) composto, composição, e, uso dos mesmos

Abstract

(PT) composto, composição, e, uso dos mesmosa presente invenção provê novos succinatos de células permeáveis a células e precursores permeáveis de succinato destinadas a aumentar a produção de atp em mitocôndrias. a parte principal de atp produzida e utilizada na célula eucariótica origina da fosforilação oxidativa mitocondrial, um processo para o qual elétrons de alta energia são providos pelo ciclo de krebs. nem todos os intermediários do ciclo de krebs são prontamente permeáveis à membrana celular, um deles sendo succinato. a provisão dos novos succinatos permeáveis a células é considerada para permitir a passagem através da membrana celular e, assim, os succinatos permeáveis a células podem ser usados para melhorar a saída de atp mitocondrial.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
323	Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
281	Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
417	Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

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1. BR112016023086 - composto, composição, e, uso dos mesmos

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q	SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19	Preparations for care of the skin

Y	SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02	TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
A	TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50	in human health protection, e.g. against extreme weather
30	Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
327	Thiocarboxylic acids
20	Esters of monothiocarboxylic acids
32	having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
34	with amino groups bound to the same hydrocarbon radicals

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800	Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
10	General cosmetic use