BR112014017633 composição farmacêutica oral e formulação compreendendo dita composição

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Brazil

Application Number 112014017633

Application Date 14.02.2013

Publication Number 112014017633

Publication Date 20.06.2017

Publication Kind A8

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Applicants TAIHO PHARMACEUTICAL CO., LTD.

Inventors TETSUO OGATA
YOSHITO OHNISHI

Agents RANA GOSAIN

Priority Data 2012-031144 15.02.2012 JP

Title

(PT) composição farmacêutica oral e formulação compreendendo dita composição

Abstract

(PT) composição farmacêutica oral e formulação compreendendo dita composição. a presente invenção provê uma composição farmacêutica oral contendo ftd e tpi que pode ser administrada por via oral e é estável mesmo em condições de alta umidade. é provida uma composição farmacêutica oral que compreende (alfa), (alfa), (alfa)-trifluorotimidina e cloridrato de 5-cloro-6-(2-iminopirrolidina-1-il)metil- 2,4(1h,3h)-pirimidinadiona como um ingrediente ativo; e que é substancialmente livre de um aditivo incluindo um sal de metal.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

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1. BR112014017633 - composição farmacêutica oral e formulação compreendendo dita composição

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505	Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
513	having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, tablets, ; discs, rods
2004	Excipients; Inactive ingredients
2022	Organic macromolecular compounds
205	Polysaccharides, e.g. alginate, gums; Cyclodextrin
2054	Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, tablets, ; discs, rods
2004	Excipients; Inactive ingredients
2022	Organic macromolecular compounds
205	Polysaccharides, e.g. alginate, gums; Cyclodextrin
2059	Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7068	having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
7072	having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine