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1. (AU2010257453) Neuroprotective effective compound

Office : Australia
Application Number: 2010257453 Application Date: 24.12.2010
Publication Number: 2010257453 Publication Date: 20.01.2011
Publication Kind : B2
IPC:
A61K 48/00
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
CPC:
A61K 48/005
A61K 38/1875
Applicants: Kolon TissueGene, Inc.
Inventors:
Agents: FPA Patent Attorneys Pty Ltd
Priority Data: 60/595,342 23.06.2005 US
Title: (EN) Neuroprotective effective compound
Abstract: front page image
(EN) The present application discloses a method of preventing degeneration of nerve, which includes: a) generating a recombinant viral or plasmid vector comprising a DNA sequence encoding a member of a transforming growth factor superfamily or neurotrophic factor proteins operatively linked to a promoter; b) transfecting in vitro a population of cultured cells with the recombinant vector, resulting in a population of the cultured cells; and c) transplanting the transfected cells to an area near an injured nerve, such that expression of the DNA sequence within the area near the injured nerve causes prevention or degeneration of the nerve.
Also published as:
KR1020080038310KR1020100074340EP1904113JP2009506982CN101232904CA2613551
JP2014088425KR1020130101595KR1020140132010ES2562243KR1020160021458DK1904113
CN106177996AU2006261889IN10145/DELNP/2007KR1020180057737WO/2007/002512