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1. (AU2013273711) Method of making small liposomes

Office : Australia
Application Number: 2013273711 Application Date: 19.12.2013
Publication Number: 2013273711 Publication Date: 16.01.2014
Publication Kind : B2
IPC:
C07K 14/775
A61K 9/127
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
775
Apolipopeptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
Applicants: Oncothyreon, Inc.
Inventors:
Agents: Davies Collison Cave Pty Ltd
Priority Data: 61/138,353 17.12.2008 US
Title: (EN) Method of making small liposomes
Abstract: front page image
(EN) Liposomes of constrained particle size are prepared by substantially continuously mixing substantially continuously flowing streams of water, and of an organic solvent contain lipid(s) capable of forming liposomes, and cooling the mixture so liposomes form, the ratio of the flow rate of the stream of water to the flow rate of the stream of organic solvent, and the rate of cooling of said mixture, being controlled so as to obtain a preparation of liposomes such that at least about 90% of the liposomes are of a particle size less than about 200 nm.
Also published as:
EP2367532SG172257JP2012512260US20120034294CN102256595CA2747182
EA201100829JP2014224127MX2011006562KR1020110094114CN105935352AU2009333177
IN2997/KOLNP/2011BRPI0923001WO/2010/078045