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1. AU2001286875 - Bridged nicotine compounds for use in the treatment of cns pathologies

Office
Australia
Application Number 2001286875
Application Date 30.08.2001
Publication Number 2001286875
Publication Date 22.11.2001
Publication Kind A
IPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants University of Kentucky Research Foundation
Inventors Crooks, Peter
Dwoskin, Linda
Grinevich, Vladimir
Xu, Rui
Priority Data 60228766 30.08.2000 US
Title
(EN) Bridged nicotine compounds for use in the treatment of cns pathologies
Abstract
(EN)
Pharmaceutical compounds commprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) having selective antagonist properties at $g(a)3$g(b)2-containing nicotinic receptor subtypes, and compositions containing these compounds. The compounds and compositions are used to treat central nervous system pathologies.

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