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1. AU2001232305 - Novel protein having signal sequence

Office
Australia
Application Number 2001232305
Application Date 15.02.2001
Publication Number 2001232305
Publication Date 26.04.2001
Publication Kind A
IPC
C12N 15/12
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/705
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
Applicants Chugai Seiyaku Kabushiki Kaisha
Inventors Ashihara, Motooki
Ito, Hirotaka
Ohtomo, Toshihiko
Saito, Mikiyoshi
Tsuchiya, Masayuki
Priority Data 2000-41459 15.02.2000 JP
Title
(EN) Novel protein having signal sequence
Abstract
(EN) A DNA encoding a novel protein SMAP-1, which has a signal sequence, is successfully isolated by screening a cDNA library originating in human fetal hepatocytes with the use of an originally developed TMT method. The expression characteristics and structural characteristics of SMAP-1 suggest that it is a molecule having an important role in vivo.