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1. (AU1998074352) Compositions for enhancing immunosuppressants' pharmaceutical acti vities

Office : Australia
Application Number: 74352/98 Application Date: 18.05.1998
Publication Number: 1998074352 Publication Date: 04.02.1999
Publication Kind : A
Prior PCT appl.: Application Number:FI1998000418 ; Publication Number: Click to see the data
IPC:
A61K 38/00
A61K 38/13
A61K 38/21
A61P 43/00
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12
Cyclic peptides
13
Cyclosporins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
21
Interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
CPC:
A61K 38/13
A61K 38/212
Applicants: Dolgikh, Dmitry Aleksandrovich
Kirpichnikov, Mikhail Petrovich
Korpela, Timo Kalevi
Navolotskaya, Elena Vitalievna
Vasilenko, Raisa Nikolaevna
Zavialov, Vladimir Petrovich
Inventors: Dolgikh, Dmitry Aleksandrovich
Kirpichnikov, Mikhail Petrovich
Korpela, Timo Kalevi
Navolotskaya, Elena Vitalievna
Vasilenko, Raisa Nikolaevna
Zavialov, Vladimir Petrovich
Priority Data: 972121 19.05.1997 FI
Title: (EN) Compositions for enhancing immunosuppressants' pharmaceutical acti vities
Abstract:
(EN) The present invention provides the compositions for efficient amplification of immunosuppressive activity of cyclosporins, FK506 or rapamycin to decrease therapeutical dose of immunosuppressants, and as the consequence to avoid their undesirable side effects during organ and tissue transplantation, and treatment of different diseases. These compositions include cyclosporins, FK506 or rapamycin and biologically active peptides corresponding to the high-affinity binding/anti-lymphoproliferative site of IFNs-a,b,w,t, or recombinant proteins having the amino acid sequences corresponding to the said site.
Also published as:
EP0981359JP2001526675 WO/1998/052594