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1. AU1996061182 - Serum amyloid A protein

Office Australia
Application Number 61182/96
Application Date 03.06.1996
Publication Number 1996061182
Publication Date 06.02.1997
Publication Kind A
IPC
A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
CPC
A61K 38/1709
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
1703from vertebrates
1709from mammals
Applicants Queen's University at Kingston
Agents FPA Patent Attorneys Pty Ltd
Priority Data 458054 01.06.1995 US
Title
(EN) Serum amyloid A protein
Abstract
(EN)
A method is provided for potentiating the release and collection of cholesterol from inflammatory or atherosclerotic sites $i(in vivo), the method including the steps of increasing the affinity of high-density lipoprotein for macrophages by administering to a patient an effective amount of a composition comprising a compound selected from the group consisting of native serum amyloid A (SAA) and a ligand having SAA properties thereby increasing the affinity of high density lipoprotein (HDL) for macrophages and potentiating release and collection of cholesterol.

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