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1. (AU1991069579) Chromogenic substrate

Office : Australia
Application Number: 69579/91 Application Date: 03.12.1990
Publication Number: 1991069579 Publication Date: 17.09.1992
Publication Kind : A
Prior PCT appl.: Application Number:SE1990000797 ; Publication Number: Click to see the data
IPC:
C07K 1/02
C07K 1/113
C07K 5/08
C07K 5/083
C07K 5/093
C07K 5/10
C07K 5/103
C07K 11/00
C12Q 1/37
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
02
in solution
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
107
by chemical modification of precursor peptides
113
without change of the primary structure
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
083
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
093
the side chain of the first amino acid containing more carboxyl groups than amino groups, or derivatives thereof, e.g. Asp, Glu, Asn
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
10
Tetrapeptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
10
Tetrapeptides
103
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
11
Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
34
involving hydrolase
37
involving peptidase or proteinase
CPC:
C07K 11/00
C07K 5/101
Y02P 20/55
Applicants: Kabi Diagnostica AB
Inventors: Arielly, Salo
Priority Data: 8904188 12.12.1989 SE
Title: (EN) Chromogenic substrate
Abstract:
(EN) The invention relates to novel peptide derivatives with the formula: R1-A1-A2-A3-A4-R2 or its salt, wherein R1 = H or a protective group; A1 = H, Ile, Leu or Val; A2 = Glu, Asp, Ser, Thr; A3 = Gly or Glyc; A4 = Arg or Lys; R2 = 4-nitro aniline with the proviso that A3 is Gly when A4 is Lys and that A3 is Glyc when A4 is Arg. The invention also discloses the process for the preparation of the peptide derivatives, the method for the determination of the bacterial endotoxins by the use of the invented peptide derivatives and the use of these derivatives for determination of bacterial endotoxins.
Also published as:
ES2098344EP0505428US5334703JPH05506209DE000069030102WO/1991/009052