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1. (US20160224748) Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions

Office : United States of America
Application Number: 15098027 Application Date: 13.04.2016
Publication Number: 20160224748 Publication Date: 04.08.2016
Grant Number: 10073952 Grant Date: 11.09.2018
Publication Kind : B2
IPC:
G01N 33/48
G06F 19/00
C40B 30/02
G06F 19/28
G06F 19/24
G16H 50/20
G06G 7/58
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
C CHEMISTRY; METALLURGY
40
COMBINATORIAL TECHNOLOGY
B
COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
30
Methods of screening libraries
02
In silico screening
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
28
for programming tools or database systems, e.g. ontologies, heterogeneous data integration, data warehousing or computing architectures
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
24
for machine learning, data mining or biostatistics, e.g. pattern finding, knowledge discovery, rule extraction, correlation, clustering or classification
[IPC code unknown for G16H 50/20]
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
G
ANALOGUE COMPUTERS
7
Devices in which the computing operation is performed by varying electric or magnetic quantities
48
Analogue computers for specific processes, systems, or devices, e.g. simulators
58
for chemical processes
CPC:
C40B 30/02
G06F 19/24
G06F 19/28
G06F 19/3418
G06F 19/345
G16H 50/20
Y02A 90/26
Applicants: uBiome, Inc.
Inventors: Zachary Apte
Daniel Almonacid
Jessica Richman
Siavosh Rezvan Behbahani
Agents: Kilpatrick Townsend & Stockton LLP
Priority Data:
Title: (EN) Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Abstract: front page image
(EN)

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.